PCL, polycaprolactone, has good biodegradability, biocompatibility and non-toxicity, and is widely used as a medical biodegradable material and a drug controlled release system, and can be used in tissue engineering as a drug sustained release system. Used as a drug slow-release system.
Polycaprolactone (PCL) is a kind of thermoplastic crystalline polyester obtained by ring-opening polymerization of caprolactone with glycol as initiator. PCL has a melting point of 59~64°C and a glass transition temperature of about -60~65 °C. It is a white opaque solid with certain rigidity and strength. It has typical resin characteristics and has good compatibility with polymer materials. It can be used as a modifier to improve certain properties of other polymers; it is easily soluble in solvents such as toluene, tetrahydrofuran, ethyl acetate and dichloromethane, and it is easy to form a film. Since the repeating unit of PCL has 5 non-polar methylene groups and one polar ester group, it has good flexibility and processability, while the product has shape memory. However, the lack of mechanical strength of PCL limits its application and development.
